President Donald Trump, joined by Robert F. Kennedy Jr., Dr. Jay Bhattacharya (NIH), Dr. Marty Makary (FDA), Dr. Mehmet Oz (CMS), and Dr. Dorothy Fink (HHS), announced new federal initiatives targeting autism causes and treatments. The press conference blended government action steps, medical guidance, and emotional testimony from parents.
Research assistance from ChatGPT AI.
Key Announcements
- Tylenol (Acetaminophen) and Autism
- Trump and Kennedy highlighted studies suggesting prenatal Tylenol use may increase autism and ADHD risk.
- The FDA will issue physician notices and begin updating labels to warn of risks in pregnancy.
- Pregnant women were advised to avoid Tylenol unless medically necessary (e.g., high fever).
- Vaccine Scheduling and Ingredients
- Trump called for vaccines to be administered in smaller, spread-out doses rather than all at once.
- He recommended separating MMR (measles, mumps, rubella) shots rather than using a combined dose.
- He urged removal of mercury and aluminum adjuvants from vaccines.
- He opposed giving newborns the Hepatitis B vaccine, suggesting it should be delayed until adolescence.
- Leucovorin Therapy
- The FDA will approve label changes for leucovorin, a folate-related prescription drug, as a treatment for some children with autism who show folate deficiency.
- NIH and CMS will coordinate to ensure Medicaid and CHIP cover leucovorin prescriptions.
- Clinical data collection will be expanded to monitor its effectiveness.
- Autism Data Science Initiative (NIH)
- NIH announced 13 new grants under a \$50 million “Autism Data Science Initiative.”
- Research will focus on exposomics (environmental exposures), nutrition, and pregnancy-related factors alongside genetics.
Political and Rhetorical Themes
- Trump framed autism as a public health “crisis” and claimed its rise was “artificially induced.”
- He accused the medical establishment and pharmaceutical industry of suppressing evidence and misleading parents.
- Kennedy echoed this, contrasting “politicized science” with the administration’s “radical transparency.”
- Both men emphasized listening to parents who believe vaccines harmed their children.
Personal Testimonies
Two mothers spoke about raising autistic children—one profoundly affected, one higher-functioning—expressing gratitude to Trump and Kennedy for “finally listening” after years of dismissal by previous administrations.
Media and Question Period
- Reporters pressed Trump and Kennedy on conflicts between their statements and medical consensus (e.g., the American College of Obstetricians and Gynecologists calling acetaminophen safe).
- Trump dismissed such objections as “establishment” resistance and insisted his recommendations posed “no downside.”
- Questions also focused on CHIP/Medicaid funding and drug availability.
Closing Emphasis
Trump ended by underscoring three points:
- Pregnant women should not take Tylenol unless absolutely unavoidable.
- Infants should not be given Tylenol post-vaccination.
- Vaccines should be separated and spread over multiple visits.
He called these steps “the most important thing” of his presidency, above even tax cuts or inflation control.
Fact-Checking the September 22, 2025 White House Press Conference on Autism
A. Acetaminophen (Tylenol) in Pregnancy and Autism/ADHD
Claim: Tylenol use in pregnancy increases the risk of autism and ADHD; FDA will update labels and warn physicians.
Facts:
- The FDA has initiated a process to update acetaminophen labeling and issue physician notices, but stated causality is unproven (FDA, 2025).
- Some meta-analyses report modest associations (Bishop et al., 2023; Masarwa et al., 2018). However, a 2024 Danish sibling-control study found no causal link (Axelsson et al., 2024).
- Professional bodies (ACOG, 2021; SOGC, 2025; WHO, 2025) maintain that acetaminophen is acceptable in pregnancy when clinically needed.
Bottom line: Evidence is mixed. Avoidance may pose risks (untreated fever). Presenting the science as settled is misleading.
B. Avoiding Acetaminophen After Infant Vaccination
Claim: Parents should not give Tylenol to infants after vaccines.
Facts:
- Some evidence suggests prophylactic acetaminophen (before/at vaccination) may slightly reduce antibody responses.
- Therapeutic use after vaccination for fever or pain has not been shown to increase autism risk (CDC, 2024).
Bottom line: No current U.S. guideline recommends blanket avoidance.
C. Vaccines, Autism, and Spacing/Separating Doses
Claim: Autism is linked to vaccines; MMR doses should be separated; Hepatitis B birth dose should be delayed.
Facts:
- Multiple large studies show no link between vaccines (including MMR) and autism (CDC, 2024; Johns Hopkins, 2025; WHO, 2025).
- Spacing vaccines increases vulnerability without benefit.
- A recent CDC panel (Sept. 2025) advised against the combined MMRV shot under age 4 due to febrile seizure risk—not autism (Reuters, 2025).
- The Hepatitis B birth dose remains a CDC/ACIP recommendation, with no link to autism (CDC, 2025).
Bottom line: Claims that spacing or separating vaccines prevents autism are unsupported.
D. “Mercury” and Aluminum in Vaccines
Claim: Mercury and aluminum in vaccines contribute to autism.
Facts:
- Thimerosal (ethyl-mercury) was removed from routine U.S. childhood vaccines in 2001, except some flu shots (CDC, 2024).
- Aluminum adjuvants are safe; no evidence links them to autism (WHO GACVS, 2012). Some observational studies noted possible links to asthma, but not autism (Glanz et al., 2022).
Bottom line: Mercury is already removed from childhood vaccines; aluminum is not linked to autism.
E. Leucovorin (Folinic Acid) as Autism Treatment
Claim: FDA is approving leucovorin for autism treatment.
Facts:
- Small clinical trials suggest folinic acid helps some autistic children with folate receptor autoantibodies (Frye et al., 2016; Rossignol & Frye, 2021).
- Evidence is promising but limited; broad FDA approval as a general autism therapy is not yet established (Reuters, 2025).
Bottom line: Encouraging early results, but benefits apply mainly to specific subgroups.
F. Autism Prevalence (“1 in 10,” “1 in 12,” “1 in 31”)
Claim: Autism affects as many as 1 in 10 or 12 children.
Facts:
- The latest CDC data (2022 cohort, released April 2025) shows prevalence at 1 in 31 nationally (CDC, 2025).
- Some local estimates are higher (e.g., 1 in 19), but not national figures.
Bottom line: The “1 in 10–12” statistic exaggerates prevalence.
Overall Assessment
- Accurate/partly accurate: FDA label changes on acetaminophen, NIH Autism Data Science Initiative, early evidence for leucovorin in subsets.
- Misleading/unsupported: Claims linking vaccines or ingredients to autism, spacing/separating vaccines as prevention, Tylenol-autism link as settled science, inflated prevalence numbers.
References
- American College of Obstetricians and Gynecologists (ACOG). (2021). Response to consensus statement on paracetamol use during pregnancy. https://www.acog.org
- Axelsson, O., et al. (2024). Prenatal acetaminophen exposure and risk of autism spectrum disorder: Sibling-controlled cohort study. JAMA Psychiatry.
- Bishop, D. V. M., et al. (2023). In utero acetaminophen exposure and child neurodevelopmental outcomes. Paediatric and Perinatal Epidemiology, 37(2), 268–290.
- Centers for Disease Control and Prevention (CDC). (2024). Autism and vaccines: Vaccine safety. https://cdc.gov/vaccine-safety
- Centers for Disease Control and Prevention (CDC). (2025). Data and statistics on autism spectrum disorder. https://cdc.gov/autism
- Food and Drug Administration (FDA). (2025). FDA responds to evidence of possible association between autism and acetaminophen use during pregnancy. https://fda.gov
- Frye, R. E., et al. (2016). Folinic acid improves verbal communication in children with autism. Molecular Psychiatry, 21(2), 241–250.
- Glanz, J. M., et al. (2022). Aluminum exposure from vaccines and risk of persistent asthma. Academic Pediatrics, 22(8), 1251–1261.
- Johns Hopkins Bloomberg School of Public Health. (2025). The evidence on vaccines and autism. https://publichealth.jhu.edu
- Masarwa, R., et al. (2018). Prenatal acetaminophen exposure and risk for ADHD and ASD: Systematic review and meta-analysis. American Journal of Epidemiology, 187(8), 1817–1827.
- Reuters. (2025, September 18). Kennedy advisers vote against MMRV shot for children under 4. https://www.reuters.com
- Reuters. (2025, September 22). Why is leucovorin being considered an autism treatment? https://www.reuters.com
- Rossignol, D. A., & Frye, R. E. (2021). Cerebral folate deficiency, folate receptor alpha autoantibodies, and leucovorin treatment in ASD: Meta-analysis. Journal of Personalized Medicine, 11(11), 1141.
- Society of Obstetricians and Gynaecologists of Canada (SOGC). (2025). Statement on acetaminophen use in pregnancy. https://sogc.org
- WHO Global Advisory Committee on Vaccine Safety. (2012). Aluminium adjuvants: Safety review. https://who.int
- World Health Organization (WHO). (2025, September 23). WHO says evidence ‘inconsistent’ of link between autism and paracetamol use in pregnancy. Reuters.